[kloxahSILLin Pregnancy Category B

Apo-Cloxi M, Cloxapen, Novo-Cloxin M, Nu-CLoxi M, Orbenin M, Taro-Cloxacillin M, Tegopen [Rx] Classification: Antibiotic, penicillin

See also Anti-Infectives and Penicillins.

Action/Kinetics: Resistant to penicillinase and is acid stable. Peak plasma levels: 7-15 mcg/mL after 30-60 min. tV2: 30 min. Protein binding: 88%-96%. Well absorbed from GI tract. Mostly excreted in urine, but some excreted in bile. Uses: Infections caused by penicilli-nase-producing staphylococci, including pneumococci, group A beta-hemolytic streptococci, and penicillin G-sensitive staphylococci. Contraindications: Hypersensitiv-ity to penicillins.

Special Concerns: Hypersensitivity to cephalosporins.

Side Effects: See also Anti-Infectives and Penicillins. Drug Interactions

Probenecid / T Cloxacillin concentrations

See also Anti-Infectives and Penicillins.

How Supplied: Capsule: 250 mg, 500 mg; Powder for reconstitution: 125 mg/5 mL


Was this article helpful?

0 0

Post a comment