Acarbose

[ah-KAR-bohs] Pregnancy Category: B

Prandase M, Precose [Rx] Classification: Antidiabetic agent

Action/Kinetics: Acarbose delays the intestinal absorption of glucose resulting in a smaller increase in blood glucose following meals. Approximately 65% of an oral dose of acarbose remains in the GI tract, which is the site of action. Metabolized in the GI tract by both intestinal bacteria and intestinal enzymes. The acar-bose and metabolites that are absorbed are excreted in the urine. Uses: Used alone, with diet control, to decrease blood glucose in type 2 diabetes mellitus. Also, used with a sulfonylurea when diet plus either acarbose or a sulfonylurea alone do not control blood glucose adequately.

Contraindications: Diabetic ketoa-cidosis, cirrhosis, inflammatory bowel disease, colonic ulceration, partial intestinal obstruction or predisposition to intestinal obstruction, chronic intestinal diseases associated with marked disorders of digestion or absorption, conditions that may deteriorate as a result of increased gas formation in the intestine. In significant renal dysfunction. Severe, persistent bradycardia. Lactation. Special Concerns: Safety and efficacy have not been determined in children. Acarbose does not cause hypo-glycemia; however, sulfonylureas and insulin can lower blood glucose sufficiently to cause symptoms or even life-threatening hypoglycemia. Side Effects: GI: Abdominal pain, diarrhea, flatulence. GI side effects may be severe and be confused with paralytic ileus. Drug Interactions Charcoal / l Effect of acarbose Digestive enzymes / l Effect of acar-bose

Digoxin / l Serum digoxin levels Insulin / T Hypoglycemia which may cause severe hypoglycemia Sulfonylureas / T Hypoglycemia which may cause severe hypoglyce-mia

How Supplied: Tablet: 50 mg, 100 mg

Dosage-

Supplements For Diabetics

Supplements For Diabetics

All you need is a proper diet of fresh fruits and vegetables and get plenty of exercise and you'll be fine. Ever heard those words from your doctor? If that's all heshe recommends then you're missing out an important ingredient for health that he's not telling you. Fact is that you can adhere to the strictest diet, watch everything you eat and get the exercise of amarathon runner and still come down with diabetic complications. Diet, exercise and standard drug treatments simply aren't enough to help keep your diabetes under control.

Get My Free Ebook


Post a comment