Anspor Velosef [Rx Classification Cephalosporin firstgeneration

See also Anti-Infectives and Cephalo-sporins.

Action/Kinetics: Similar to cephalexin. Rapidly absorbed PO or IM (30 min-2 hr); 60%-90% excreted after 6 hr. Peak serum levels: PO,

8-24 mcg/mL after 30-60 min; IM, 5.6-13.6 mcg/mL after 1-2 hr. tV2: 42-120 min; 80%-95% excreted in urine unchanged.

Uses: Infections of the respiratory tract (including lobar pneumonia, tonsillitis, pharyngitis), urinary tract (including prostatitis and enterococcal infections), skin, skin structures, and bone. Otitis media, septicemia, prophylaxis in surgery, following cesar-ean section to prevent infection. In severe infections, therapy is usually initiated parenterally. Contraindications: Hypersensitiv-ity to cephalosporins. Special Concerns: Safe use during pregnancy, of the parenteral form in infants under 1 month of age, and of the PO form in children less than 9 months of age have not been established. Hypersensitivity to penicillins. Use in renal impairment. Side Effects: See also Cephalosporins. Drug Interactions: See also Cepha-losporins.

How Supplied: Capsule: 250 mg, 500 mg; Powder for reconstitution: 125 mg/5 mL, 250 mg/5 mL

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