See also the following drug classes and individual drugs:
Agents Acting Directly on Vascular Smooth Muscle
Hydralazine hydrochloride Alpha-1-Adrenergic Blocking Agents Doxazosin mesylate Prazosin hydrochloride Terazosin
Angiotensin-II Antagonists Irbesartan Losartan potassium Valsartan
Angiotensin-Converting Enzyme Inhibitors
Benazepril hydrochloride Captopril Enalapril maleate Fosinopril sodium
Beta-Adrenergic Blocking Agents
Calcium Channel Blocking Agents Amlodipine
Centrally-Acting Agents Clonidine hydrochloride Methyldopa
Combination Drugs Used for Hypertension
Hydrochlorothiazide Miscellaneous Agents
Minoxidil, oral General Statement: The Sixth Report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure classifies BP for adults aged 18 and over as follows: Optimal as <120/<80 mm Hg, Normal as <130/<85 mm Hg, High Normal as 130-139/85-89 mm Hg, Stage 1 Hypertension as 140-159/90-99 mm Hg, Stage 2 Hypertension as 160-179/100-109 mm Hg, and Stage 3 Hypertension as 180 or greater/110 or greater mm Hg. Drug therapy is recommended depending on the BP and whether certain risk factors (e.g., smoking, dyslipidemia, diabetes, age, gender, target organ damage, clinical CV disease) are present. Life-style modification is an important component of treating hypertension, including weight reduction, reduction of sodium intake, regular exercise, cessation of smoking, and moderate alcohol intake.
The goal of antihypertensive therapy is a BP of <140/90 mm Hg, except in hypertensive diabetics where the goal is <135/85 mm Hg and those with renal insufficiency where the goal is <130/85 mm Hg. Generally speaking, the primary agents for initial monotherapy to treat uncomplicated hypertension are diuretics and beta blockers. Alternative drugs include ACE inhibitors, alpha-1 blockers, alpha-beta blocker, and calcium antagonists.
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Do You Suffer From High Blood Pressure? Do You Feel Like This Silent Killer Might Be Stalking You? Have you been diagnosed or pre-hypertension and hypertension? Then JOIN THE CROWD Nearly 1 in 3 adults in the United States suffer from High Blood Pressure and only 1 in 3 adults are actually aware that they have it.