See also Antihistamines. Action/Kinetics: Fexofenadine, a metabolite of terfenadine, is an H1-his-tamine receptor blocker. Low to no sedative or anticholinergic effects. Onset: Rapid. Peak plasma levels: 2.6 hr. t!/2, terminal: 14.4 hr. Approximately 90% of the drug is excreted through the feces (80%) and urine (10%) unchanged. Uses: Seasonal allergic rhinitis in adults and children 12 years of age and older.
Contraindications: Hypersensitiv-ity; troglitazone.
Special Concerns: Use with care during lactation. Safety and efficacy have not been determined in children less than 12 years of age. Side Effects: CNS: Drowsiness, fatigue. GI: Nausea, dyspepsia. Miscellaneous: Viral infection (flu, colds), dysmenorrhea, sinusitis, throat irritation.
Drug Interactions: No differences in side effects or the QTc interval were observed when fexofenadine was given with either erythromycin or ketoconazole.
How Supplied: Capsule: 60 mg
Was this article helpful?
Gastroesophageal reflux disease is the medical term for what we know as acid reflux. Acid reflux occurs when the stomach releases its liquid back into the esophagus, causing inflammation and damage to the esophageal lining. The regurgitated acid most often consists of a few compoundsbr acid, bile, and pepsin.