Desipramine hydrochloride

[dess-IP-rah-meen] Alti-Desipramine M, Apo-Desipramine M, Dom-Desipramine M, Norpramin, Novo-Desipramine M, Nu-Desipramine M, Pertofrane M, PMS-Desipramine M (Rx) Classification: Antidepressant, tricy-clic

See also Antidepressants, Tricyclic. Action/Kinetics: Slight anticholi-nergic and sedative effects and slight ability to cause orthostatic hypotension. Effective plasma levels: 125-300 ng/mL. ti/2: 12-24 hr. Time to reach steady state: 2-11 days. Response usually seen within the first week.

Uses: Symptoms of depression. Bulimia nervosa. To decrease craving and depression during cocaine withdrawal. To treat severe neurogenic pain. Cataplexy associated with narcolepsy. Attention deficit disorders with or without hyperactivity in children over 6 years of age.

Contraindications: Use in children less than 12 years of age. Special Concerns: Safe use during pregnancy has not been established. Safety and efficacy have not been established in children. Additional Side Effects: Bad taste in mouth, hypertension during surgery.

How Supplied: Tablet: 10 mg, 25 mg, 50 mg, 75 mg, 100 mg, 150 mg


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