Dosage

Herpes zoster infections. 500 mg q 8 hr for 7 days. Dosage reduction is recommended in clients with impaired renal function: for CCR of 40-59 mL/min, the dose should be 500 mg q 12 hr; for CCR of 20-39 mL/min, the dose should be 500 mg q 24 hr; for CCR less than 20 mL/min, the dose should be 250 mg q 48 hr. For hemodialysis clients, the recommended dose is 250 mg given after each dialysis treatment.

Recurrent genital herpes. 125 mg b.i.d. for 5 days. Should be taken within 6 hr of symptoms or le sion onset. Dosage reduction is as follows for those with impaired renal function: for CCR of 40 mL/min or greater, use the recommended dose of 125 mg b.i.d.; for CCR of 20-39 mL/min, the dose should be 125 mg q 24 hr; for CCR less than 20 mL/min, the dose should be 125 mg q 48 hr. For hemodialysis clients, the recommended dose is 125 mg given after each dialysis treatment.

Prevent outbreaks of genital herpes.

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