Drug Interactions

Acetaminophen / T Risk of hepato-toxicity due to T rate of formation of hepatotoxic acetaminophen metabolite

Alcohol / T Risk of GI ulceration or hemorrhage

Anabolic steroids / T Risk of edema Antacids / l Effect of corticoster-oids due to l absorption from GI tract

Antibiotics, broad-spectrum / Concomitant use may result in emergence of resistant strains, leading to severe infection

Anticholinergics / Combination T intraocular pressure; will aggravate glaucoma

Barbiturates / l Effect of corticos-teroids due to T breakdown by liver Ephedrine / l Effect of corticoster-oids due to T breakdown by liver Immunosuppressant drugs / T Risk of infection

Indomethacin / T Chance of GI ulceration

Ketoconazole / l Effect of corticos-teroids due to T rate of clearance Muscle relaxants, nondepolarizing / l Effect of muscle relaxants Neuromuscular blocking agents / T Risk of prolonged respiratory depression or paralysis NSAIDs / T Risk of GI hemorrhage or ulceration

Phenobarbital / l Effect of corticos-teroids due to T breakdown by liver Phenytoin / l Effect of corticoster-oids due to T breakdown by liver Rifampin / l Effect of corticoster-oids due to T breakdown by liver Salicylates / Both are ulcerogenic; also, corticosteroids may l blood salicylate levels

Streptozocin / T Risk of hyperglyce-mia

Tricyclic antidepressants / T Risk of mental disturbances

Anxiety and Depression 101

Anxiety and Depression 101

Everything you ever wanted to know about. We have been discussing depression and anxiety and how different information that is out on the market only seems to target one particular cure for these two common conditions that seem to walk hand in hand.

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