Moderate to high sedative effects.
Significant anticholinergic and anti-emetic effects. Low incidence of GI side effects. Examples: Clemastine, diphenhydramine.
3. Alkylamines. Among the most potent antihistamines. Minimal sedation, moderate anticholinergic effects, and no antiemetic effects. Paradoxical excitation may also occur. Examples: Brompheniramine, chlor-pheniramine, dexchlorpheniramine.
4. Phenothiazines. Significant anti-histaminic action and sedation; high degree of both anticholinergic and antiemetic effects. Example: Pro-methazine.
5. Piperidines. Moderate antihista-minic activity, low to moderate sedation, moderate anticholinergic activity, and no antiemetic effects. Examples: Azatadine, cyproheptadine, pheninda-mine.
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