Gen Indapamide M Lozide M [Rx Classification Diuretic thiazide type

See also Diuretics, Thiazide. Action/Kinetics: Onset: 1-2 weeks after multiple doses. Peak levels: 2 hr. Duration: Up to 8 weeks with multiple doses. tVi: 14 hr. Nearly 100% is absorbed from the GI tract. Excreted through the kidneys (70% with 7% unchanged) and the GI tract (23%). Uses: Alone or in combination with other drugs for treatment of hypertension. Edema in CHF. Contraindications: Hypersensitivity, asthma, severe hepatic disease, severe renal disease. Special Concerns: Dosage has not been established in children. Geriatric clients may be more sensitive to the hypotensive and electrolyte effects.

Side Effects: See also Diuretics, Thi-azide.

Drug Interactions: See also Diuretics, Thiazide.

How Supplied: Tablet: 1.25 mg, 2.5 mg

Dosage-

Edema of CHF. Adults: 2.5 mg as a single dose in the morning. If necessary, may be increased to 5 mg/day after 1 week.

Hypertension. Adults: 1.25 mg as a single dose in the morning. If the response is not satisfactory after 4 weeks, the dose may be increased to 2.5 mg taken once daily. If the response to 2.5 mg is not satisfactory after 4 weeks, the dose may be increased to 5 mg taken once daily (however, consideration should be given to adding another antihypertensive).

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