See also Diuretics, Thiazide. Action/Kinetics: Onset: 1-2 weeks after multiple doses. Peak levels: 2 hr. Duration: Up to 8 weeks with multiple doses. tVi: 14 hr. Nearly 100% is absorbed from the GI tract. Excreted through the kidneys (70% with 7% unchanged) and the GI tract (23%). Uses: Alone or in combination with other drugs for treatment of hypertension. Edema in CHF. Contraindications: Hypersensitivity, asthma, severe hepatic disease, severe renal disease. Special Concerns: Dosage has not been established in children. Geriatric clients may be more sensitive to the hypotensive and electrolyte effects.
Side Effects: See also Diuretics, Thi-azide.
Drug Interactions: See also Diuretics, Thiazide.
How Supplied: Tablet: 1.25 mg, 2.5 mg
Edema of CHF. Adults: 2.5 mg as a single dose in the morning. If necessary, may be increased to 5 mg/day after 1 week.
Hypertension. Adults: 1.25 mg as a single dose in the morning. If the response is not satisfactory after 4 weeks, the dose may be increased to 2.5 mg taken once daily. If the response to 2.5 mg is not satisfactory after 4 weeks, the dose may be increased to 5 mg taken once daily (however, consideration should be given to adding another antihypertensive).
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Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...