Gum Chewable Tablets Coat

ed Tablets, Effervescent Tablets, Enteric-Coated Tablets, Suppositories, Tablets, Timed (Controlled) Release Tablets

Analgesic, antipyretic. Adults: 325-500 mg q 3 hr, 325-600 mg q 4 hr, or 650-1,000 mg q 6 hr. As an alternative, the adult chewable tablet (81 mg each) may be used in doses of 4-8 tablets q 4 hr as needed. Pediatric: 65 mg/kg/day (alternate dose: 1.5 g/m2/day) in divided doses q 4-6 hr, not to exceed 3.6 g/day. Alternatively, the following dosage regimen can be used: Pediat-ric, 2—3 years: 162 mg q 4 hr as needed; 4-5 years: 243 mg q 4 hr as needed; 6-8 years: 320-325 mg q 4 hr as needed; 9-10 years: 405 mg q 4 hr as needed; 11 years: 486 mg q 4 hr as needed; 12-14 years: 648 mg q 4 hr.

Arthritis, rheumatic diseases. Adults: 32-6 g/day in divided doses.

Juvenile rheumatoid arthritis. 60-110 mg/kg/day (alternate dose: 3 g/m2) in divided doses q 6-8 hr. When initiating therapy at 60 mg/kg/day, dose may be increased by 20 mg/kg/day after 5-7 days and by 10 mg/kg/day after another 5-7 days.

Acute rheumatic fever. Adults, initial: 5-8 g/day. Pediat-ric, initial: 100 mg/kg/day (3 g/m2/day) for 2 weeks; then, decrease to 75 mg/kg/day for 4-6 weeks.

Transient ischemic attacks in men.

Adults: 650 mg b.i.d. or 325 mg q.i.d. A dose of 300 mg/day may be as effective and with fewer side effects.

Prophylaxis of MI. Adults: 300 or 325 mg/day (both solid PO dosage forms-regular and buffered as well as buffered aspirin in solution). The adult chewable tablets may also be used.

Kawasaki disease. Adults: 80-180 mg/kg/day during the febrile period. After the fever re solves, the dose may be adjusted to 10 mg/kg/day.

NOTE: Doses as low as 80-100 mg/day are being studied for use in unstable angina, MI, and aortocoro-nary bypass surgery. Aspirin Regimen Bayer 81 mg with Calcium contains 250 mg calcium carbonate (10% of RDA) and 81 mg of acetylsal-icylic acid for individuals who require aspirin to prevent recurrent heart attacks and strokes.

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