Bolus

Antiarrhythmic. Adults: 50-100 mg at rate of 25-50 mg/min. Bolus is used to establish rapid therapeutic plasma levels. Repeat if necessary after 5-min interval. Onset of action is 10 sec. Maximum dose/hr: 200-300 mg.

• Infusion Antiarrhythmic.

20-50 mcg/kg at a rate of 1-4 mg/min. No more than 200-300 mg/hr should be given. Pediatric, loading dose: 1 mg/kg IV or intratra-cheally q 5-10 min until desired effect reached (maximum total dose: 5 mg/kg).

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