Lamivudine Zidovudine

((lah-MIH-vyou-deen, zye-DOH-vyou-deen)] Pregnancy Category: C Combivir (Rx)

Classification: Antiviral drug combination

See also Lamivudine, Zidovudine, and Antiviral Drugs. Content: Each Combivir tablet contains: Antiviral: Lamivudine, 150 mg and Antiviral: Zidovudine, 300 mg. Action/Kinetics: Both drugs are reverse transcriptase inhibitors with activity against HIV. Combination results in synergistic antiretroviral effect. Each drug is rapidly absorbed. Uses: Treatment of HIV infection. Contraindications: Use in clients requiring dosage reduction, children less than 12 years of age, CCR less than 50 mL/min, body weight less than 50 kg, and in those experiencing dose-limiting side effects. Side Effects: See individual drugs. Drug Interactions: See individual drugs.


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