Midazolam hydrochloride

[my-DAYZ-oh-lam] Pregnancy Category: D Versed (C-IV) (Rx)

Classification: Benzodiazepine sedative; adjunct to general anesthesia

See also Sedative-Hypnotics (Anti-anxiety)/Antimanic Drugs. Action/Kinetics: Short-acting benzodiazepine with sedative—general anesthetic properties. Depresses the response of the respiratory system to carbon dioxide stimulation, which is more pronounced in clients with COPD. Possible mild to moderate decreases in CO, mean arterial BP, SV, and systemic vascular resistance. HR may rise somewhat in those with slow HRs (< 65/min) and decrease in others (especially those with HRs more than 85/min). Onset, IM: 15 min; IV: 2—2.5 min for induction (if combined with a preanesthetic narcotic, induction is about 1.5 min). If preanesthetic medication (morphine) is given, the Peak plasma

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