Oral Solution Tablets



Adults, initial: 20-80 mg/day as a single dose. For resistant cases, dosage can be increased by 20-40 mg q 6-8 hr until desired diuretic response is attained. Maximum daily dose should not exceed 600 mg. Pe-diatric, initial: 2 mg/kg as a single dose; then, dose can be increased by 1-2 mg/kg q 6-8 hr until desired response is attained (up to 5 mg/kg may be required in children with nephrotic syndrome; maximum dose should not exceed 6 mg/kg). A dose range of 0.5-2 mg/kg b.i.d. has also been recommended.

Hypertension. Adults, initial: 40 mg b.i.d. Adjust dosage depending on response.

CHF and chronic renal failure. Adults: 2-2.5 g/day.

Antihypercalcemic. Adults: 120 mg/day in one to three doses. • IV, IM


Adults, initial: 20-40 mg; if response inadequate after 2 hr, increase dose in 20-mg increments. Pediatric, initial: 1 mg/kg given slowly; if response inadequate after 2 hr, increase dose by 1 mg/kg. Doses greater than 6 mg/kg should not be given.

Antihypercalcemic. Adults: 80-100 mg for severe cases; dose may be repeated q 1-2 hr if needed. • IV

Acute pulmonary edema. Adults: 40 mg slowly over 1-2 min; if response inadequate after 1 hr, give 80 mg slowly over 1-2 min. Concomitant oxygen and digitalis may be used.

CHF, chronic renal failure. Adults: 2-2.5 g/day. For IV bolus injections, the maximum should not exceed 1 g/day given over 30 min.

Hypertensive crisis, normal renal function. Adults: 40-80 mg.

Hypertensive crisis with pulmonary edema or acute renal failure. Adults: 100-200 mg.

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