Oral Suspension Tablets Chewable Tablets Extended Release Tablets

Anticonvulsant. Adults and children over 12 years, initial: 200 mg b.i.d. on day 1 (100 mg q.i.d. of suspension). Increase by 200 mg/day at weekly intervals until best response is attained. Divide total dose and administer q 6—8 hr; the extended-release tablets may be used for twice-daily dosing instead of dosing 3 or 4 times a day. Maximum dose, children 12-15 years: 1,000 mg/day; adults and children over 15 years: 1,200 mg/day. Maintenance: decrease dose gradually to minimum effective level, usually 800-1,200 mg/day. Children, 6-12 years: initial, 100 mg b.i.d. on day 1 (50 mg q.i.d. of suspension); then, increase slowly, at weekly intervals, by 100 mg/day;

dose is divided and given q 6-8 hr. Daily dose should not exceed 1,000 mg. Maintenance: 400-800 mg/day. Children, less than 6 years: 10-20 mg/kg/day in two to three divided doses; dose can be increased slowly in weekly increments to maintenance levels of 250-300 mg/day (not to exceed 400 mg/day).

Trigeminal neuralgia. Initial: 100 mg b.i.d. on day 1 (50 mg q.i.d. of suspension); increase by no more than 200 mg/day, using increments of 100 mg q 12 hr as needed, up to maximum of 1,200 mg/day. Maintenance: Usual: 400-800 mg/day (range: 200-1,200 mg/day). Attempt discontinuation of drug at least 1 time q 3 months.

Restless legs syndrome. 100-300 mg at bedtime.

Nonhereditary chorea in children. 15-25 mg/kg/day.

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