[spar-FLOX-ah-sin] Pregnancy Category: C Zagam [Rx]

Classification: Fluoroquinolone antibiotic

See also Fluoroquinolones. Action/Kinetics: Well absorbed. Peak serum levels: 4-5 hr. 50% excreted in the urine. Uses: Community acquired pneumonia due to Chlamydia pneumoniae, Haemophilus influenzae, Haemophilus parainfluenzae, Moraxella catarrhalis, Mycoplasma pneumoniae, or Streptococcus pneumoniae. Acute bacterial exacerbations of chronic bronchitis caused by C. pneumoniae, Enterobacter cloacae, H. influenzae, H. parainfluenzae, Klebsiella pneumoniae, M. catarrhalis, Staphylococ-cus aureus, or S. pneumoniae. Contraindications: Hypersensitiv-ity, photosensitivity, disopyramide, amiodarone, and class Ia and III antiarrhythmics, terfenadine, bepri-dil; patients with prolonged Qtc intervals, hypokalemia, significant bradycardia

Special Concerns: Safety and efficacy have not been determined in children less than 18 years of age. Side Effects: See also Fluoroquinolones.

Drug Interactions: Avoid concurrent use with erythromycin, terfena-dine, tricyclic antidepressants, phen-othiazines.

Antacids / l Absorption of antacids How Supplied: Tablets: 200 mg


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