Tablets Enalapril

Antihypertensive in clients not taking diuretics.

Initial: 5 mg/day; then, adjust dosage according to response (range: 10-40 mg/day in one to two doses).

Antihypertensive in clients taking diuretics.

Initial: 2.5 mg. Since hypotension may occur following the initiation of enalapril, the diuretic should be discontinued, if possible, for 2-3 days before initiating enalapril. If BP is not maintained with enalapril alone, diuretic therapy may be resumed.

Adjunct with diuretics and digitalis in heart failure. Initial: 2.5 mg 1-2 times/day; then, depending on the response, 5-20 mg/day in two divided doses. Dose should not exceed 40 mg/day. Dosage must be adjusted in clients with renal impairment or hyponatremia.

In clients with impaired renal function.

Initial: 5 mg/day if CCR ranges between 30 and 80 mL/min and serum creatinine is less than 3 mg/dL; 2.5 mg/day if CCR is less than 30 mL/min and serum creatinine is more than 3 mg/dL and in dialysis clients on dialysis days.

Renal impairment or hyponatremia.

Initial: 2.5 mg/day if serum sodium is less than 130 mEq/L and serum creatinine is more than 1.6 mg/dL. The dose may be increased to 2.5 mg b.i.d. and then 5 mg b.i.d. or higher if required; dose is given at intervals of 4 or more days. Maximum daily dose is 40 mg.

Asymptomatic LV dysfunction following MI.

2.5—20 mg/day beginning 72 hr or longer after onset of MI. Therapy is continued for 1 year or longer.

NOTE: Dosage should be decreased in clients with a CCR less than 30 mL/min and a serum creatinine level greater than 3 mg/dL. • IV (Enalaprilat)

Hypertension. 1.25 mg over a 5-min period; repeat q 6 hr.

Antihypertensive in clients taking diuretics.

Initial: 0.625 mg over 5 min; if an adequate response is seen after 1 hr, administer another 0.625-mg dose. Thereafter, 1.25 mg q 6 hr.

Clients with impaired renal function.

Give enalaprit, 1.25 mg q 6 hr for clients with a CCR more than 30 mL/min and an initial dose of 0.625 mg for clients with a CCR less than 30 mL/min. If there is an adequate response, an additional 0.625 mg may be given after 1 hr; thereafter, additional 1.25-mg doses can be given q 6 hr. For dialysis clients, the initial dose is 0.625 mg q 6 hr.

Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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