Essential hypertension. Initial: 6.25 mg b.i.d. If this is tolerated, using standing systolic pressure measured about 1 hr after dosing, maintain the dose for 7-14 days. Then, increase to 12.5 mg b.i.d., if necessary, based on trough BP, using standing systolic pressure 2 hr after dosing. This dose should be maintained for 7-14 days and can then be adjusted upward to 25 mg b.i.d. if necessary and tolerated. The total daily dose should not exceed 50 mg.
Congestive heart failure. Initial: 3.125 mg b.i.d. for 2 weeks. If this is tolerated, increase to 6.25 mg b.i.d. Dosing is doubled every 2 weeks to the highest tolerated level, up to a maximum of 25 mg b.i.d. in those weighing less than 85 kg and 50 mg b.i.d. in those weighing over 85 kg.
Angina pectoris. 25-50 mg b.i.d.
Idiopathic cardiomyopathy. 6.25-25 mg b.i.d.
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Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...