Hypertension. Initial: 100 mcg b.i.d.; then, increase by 100-200 mcg/day until desired response is attained; maintenance: 200-600 mcg/day in divided doses (maximum: 2400 mcg/day). Tolerance necessitates increased dosage or concomitant administration of a diuretic. Gradual increase of dosage after initiation minimizes side effects. Pediatric: 50-400 mcg b.i.d.
NOTE: In hypertensive clients unable to take PO medication, cloni-dine may be administered sublin-gually at doses of 200-400 mcg/day.
Alcohol withdrawal. 300-600 mcg q 6 hr.
Atrial fibrillation. 75 mcg 1-2 times/day with or without digoxin.
5 mcg/kg/day for 8 weeks.
Constitutional growth delay in children.
Diabetic diarrhea. 100-600 mcg q 12 hr.
Gilles de la Tourette syndrome. 150-200 mcg/day.
Hyperhidrosis. 250 mcg 3-5 times/day.
Hypertensive urgency (diastolic > 120 mm Hg).
Initial: 100-200 mcg; then, 50-100 mcg q hr to a maximum of 800 mcg.
Menopausal flushing. 100-400 mcg/day.
Withdrawal from opiate dependence.
Diagnosis of pheochromocytoma. 300 mcg.
Postherpetic neuralgia. 200 mcg/day.
Reduce allergen-induced inflammation in extrinsic asthma. 150 mcg for 3 days or 75 mcg/1.5 mL saline by inhalation.
Restless leg syndrome. 100-300 mcg/day, up to 900 mcg/day.
Facilitate cessation of smoking. 150-400 mcg/day.
Ulcerative colitis. 300 mcg t.i.d.
• Transdermal Hypertension.
Initial: Use 0.1-mg system; then, if after 1-2 weeks adequate control has not been achieved, can use another 0.1-mg system or a larger system. The antihypertensive effect may not be seen for 2-3 days. The system should be changed q 7 days.
100-200 mcg/day. Diabetic diarrhea.
Menopausal flushing. 100 mcg/24-hr patch.
Facilitate cessation of smoking. 200 mcg/24-hr patch.
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