Topical Cream Ointment Westcort [Rx

Classification: Corticosteroid, naturally occurring; glucocorticoid-type

See also Corticosteroids. Action/Kinetics: Short-acting. tv2: 80—118 min. Topical products are available without a prescription in strengths of 0.5% and 1%. How Supplied: Hydrocortisone Cortisol: Balm: 1%; Cream: 0.25%, 0.5%, 1%, 2.5%; Enema: 100 mg/60 mL; Gel/jelly: 1%; Liquid: 1%; Lotion: 0.25%, 0.5%, 1%, 2%, 2.5%; Ointment: 0.5%, 1%, 2.5%; Pad: 0.5%, 1%; Solution: 1%, 2.5%; Spray: 0.5%, 1%; Tablet: 5 mg, 10 mg, 20 mg. Hydrocortisone acetate: Cream: 0.5%, 1%; Foam: 10%; Injection: 25 mg/mL, 50 mg/mL; Lotion: 1%; Oint-

258 HYDROCORTISONE

ment: 0.5%, 1%; Paste: 0.5%; Spray: 0.5%; Suppository: 25 mg. Hydrocortisone butyrate: Cream: 0.1%; Ointment: 0.1%; Solution: 0.1%. Hydrocortisone cypionate: Suspension: 10 mg/5 mL. Hydrocortisone sodium phosphate: Injection: 50 mg/mL. Hydrocortisone sodium succinate: Powder for injection: 100 mg, 250 mg, 500 mg, 1 g. Hydrocortisone valerate: Cream: 0.2%; Ointment: 0.2%.

Dosage-

Hydrocortisone

20—240 mg/day, depending on disease.

One-third to one-half the PO dose q 12 hr.

100 mg in retention enema nightly for 21 days (up to 2 months of therapy may be needed; discontinue gradually if therapy exceeds 3 weeks).

• Topical Ointment, Cream, Gel, Lotion, Solution, Spray

Apply sparingly to affected area and rub in lightly t.i.d.-q.i.d. Hydrocortisone acetate

• Intralesional, Intra-articular, Soft Tissue

5-50 mg, depending on condition.

• Intrarectal Foam

1 applicatorful (90 mg) 1-2 times/day for 2-3 weeks; then every second day.

See Hydrocortisone. Hydrocortisone buteprate

• Topical Cream

Apply a thin film to the affected area 1-2 times/day. Hydrocortisone butyrate

• Topical Cream, Ointment, Solution

Apply a thin film to the affected area b.i.d.-t.i.d.

Hydrocortisone cypionate

• Suspension

20-240 mg/day, depending on the severity of the disease. Hydrocortisone sodium phosphate

General uses. Initial: 15-240 mg/day depending on use and on severity of the disease. usually, one-half to one-third of the PO dose is given q 12 hr.

Adrenal insufficiency, acute. Adults, initial: 100 mg IV; then, 100 mg q 8 hr in an IV fluid; older children, initial: 1-2 mg/kg by IV bolus; then, 150-250 mg/kg/day IV in divided doses; infants, initial: 1-2 mg/kg by IV bolus; then, 25-150 mg/kg/day in divided doses. Hydrocortisone sodium succinate

Initial: 100-500 mg; then, may be repeated at 2-, 4-, and 6-hr intervals depending on response and severity of condition. Hydrocortisone valerate

• Topical Cream See Hydrocortisone.

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