Acth

Adrenal cortex

Cortisol 30 mg/day

Cortisol production under normal conditions

Exogenous administration

Decrease in Cortisol production with Cortisol dose < daily production

Cessation of Cortisol production with Cortisol dose > daily production

Cortisol deficiency after abrupt cessation of administration

Adrenal cortex

33 33

Morning dose Inhibition of Elimination of Start of early

_ endogenous _ exogenous _ morning

Cortisol glucocorticoid Cortisol production during daytime production

33 33

Morning dose Inhibition of Elimination of Start of early

_ endogenous _ exogenous _ morning

Cortisol glucocorticoid Cortisol production during daytime production

Glucocorticoid

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