Cooh

a-Helices

Transmembrane domains

I Agonist

XD ooa.

A. G-Protein-coupled receptor

Subunit consisting of four trans-+ membrane

K+ domains

- jpxcoccocccoco

Nicotinic acetylcholine receptor

-ŒopceecocccŒco

- jpxcoccocccoco

Subunit consisting of four trans-+ membrane

K+ domains

B. Ligand-gated ion channel

C. Ligand-regulated enzyme

Cytosol

Nucleus

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