E

EC50, 54, 60 econazole, 282 ecothiopate, 102 ecstasy, 240 ectoparasites, 292 edema, 158, 159 EDTA, 142, 264, 302, 303 efavirenz, 288 effervescent tablets, 8 efficacy, 54, 60, 61 Ehrlich, P., 3 eicosanoids, 196 eicosapentaenoate, 156 electromechanical coupling, 128, 182 electrostatic attraction, 58, 59

elimination of drugs, 32-43, 46, 47 p-blockers, 94 biotransformation, 34-39, 42

changes during drug therapy, 50, 51 exponential rate processes, 44, 45 hydrophilic drugs, 42, 43 in kidney, 40-41, 44 in liver, 18, 32-33, 44 lipophilic drugs, 42, 43 emesis, 330-331 emulsions, 8, 16 enalapril, 34 enalaprilat, 34, 124 enantiomers, 62, 63 enantioselectivity, 62 endocytosis, 24 receptor- mediated, 26, 27

endoneural space, 206 endoparasites, 292 p-endorphin, 210, 211, 212 endothelium-derived relaxing factor (EDRF), 100, 120

enflurane, 218 enkephalins, 34, 210, 211 enolic acids, 200 enoxacin, 274 entacapone, 188 Entamoeba histolytica, 274 Enterobius vermicularis, 292

enterohepatic cycle, 38, 39 enzyme induction, 32 ephedrine, 86, 87 epilepsy, 190, 191, 226 antiepileptics, 190-193 childhood, 192 treatment, 162 epinephrine, 82, 83, 260 anaphylactic shock treatment, 84, 326, 327 p-blockers and, 92 cardiac arrest treatment, 134

local anesthesia and, 206 nicotine and, 108, 109, 110

structure-activity relationships, 86, 87 epipodophyllotoxins, 298 epoxidations, 36 epoxides, 36 Epsom salts, 170 eptifibatide, 150 ergocornine, 126 ergocristine, 126 ergocryptine, 126 ergolides, 114 ergometrine, 126, 127 ergosterol, 282, 283 ergot alkaloids, 126 ergotamine, 126, 127, 322 erythromycin, 34, 267,

276, 277 erythropoiesis, 138, 139 erythropoietin, 138 ester hydrolysis, 34 estradiol, 254, 255, 257 estriol, 254, 255 estrogen, 254, 318 estrone, 254, 255 ethacrynic acid, 162 ethambutol, 280, 281 ethanol, 202, 203, 224

elimination, 44 ethinylestradiol (EE), 254,

255, 256 ethinyltestosterone, 255 ethionamide, 280 ethisterone, 254 ethosuximide, 191, 192 ethylaminobenzoate, 324 ethylenediaminetetraacet-

etilefrine, 86, 87

fleas, 292, 293

gallopamil, 122

etofibrate, 156

flecainide, 136

gallstones, 180

etomidate, 220, 221

floxacillin, 270

dissolving of, 180, 181

etoposide, 298

fluconazole, 282

ganciclovir, 285, 286

etretinate, 74

flucytosine, 282

ganglia

euphoria, 88, 210

fludrocortisone, 248, 314

nicotine action, 108, 110

expectorants, 324, 325

flukes, 292

paravertebral, 82

exponential rate processes,

flumazenil, 226, 302

prevertebral, 82

44, 45

flunarizine, 322

ganglionic blockers, 108,

extracellular fluid volume

flunisolide, 14, 250

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