H

half-life, 44

hallucinations, atropine poisoning and, 106 hallucinogens, 240, 241 halofantrine, 294, 295 haloperidol, 236, 238, 239 halothane, 218, 219 haptens, 72, 73 hay fever, 326 HDL particles, 154 heart p-blockers and, 92 cardiac arrest, 104, 134 cardiac drugs, 128-137 cardioacceleration, 104 cardiodepression, 134 cardiostimulation, 84, 85 see also angina pectoris; myocardial infarction; myocardium heart failure p-blockers and, 92 congestive, 92, 128, 130, 158, 312

treatment, 118, 124, 132, 158

Helicobacter pylori, 166

eradication of, 168, 169 hemoglobin, 138 hemolysis, 70, 72 hemosiderosis, 140 hemostasis, 142, 148 heparin, 142-146, 309, 310

hepatic elimination, 18, 32-33, 44

exponential kinetics, 44 hepatocytes, 32, 33, 154 heroin, 212

Herpes simplex viruses,

284, 286 hexamethonium, 108 hexobarbital, 222 high blood pressure, see hypertension hirudin, 150 histamine, 72, 114, 115, 166, 326 antagonists, 114 inhibitors of release, 116 receptors, 114, 230, 326 see also antihistamines

HMG CoA reductase, 154,

156, 157 Hohenheim, Theophrastus von, 2 homatropine, 107 homeopathy, 76, 77 hookworm, 292 hormone replacement therapy, 254 hormones, 20 hypophyseal, 242-243 hypothalamic, 242-243 see also specific hormones human chorionic gonado-

tropin (HCG), 252, 256 human immunodeficiency virus (HIV), 288-289 human menopausal gona-dotropin (HMG), 252, 256

hydrochlorothiazide, 162, 164

hydrocortisone, 248 hydrogel, 16, 17 hydrolysis, 34, 35 hydromorphone, 210, 214 hydrophilic colloids, 170, 171

hydrophilic cream, 16 hydrophilic drug elimination, 42, 43 hydrophobic interactions, 58, 59

hydroxyapatite, 264, 318

4-hydroxycoumarins, 144 hydroxyethyl starch, 152 hydroxylation reactions,

17-p-hydroxyprogesterone caproate, 254

5-hydroxytryptamine (5HT), see serotonin hypercalcemia, 264 hyperglycemia, 162, 258, 260

hyperkalemia, 186 hyperlipoproteinemia, 154-157 treatment, 154 hyperpyrexia, 202 hypersensitivity, 70

hypertension therapy, 312-313 a-blockers, 90 ACE inhibitors, 124, 312 p-blockers, 92, 312 calcium antagonists, 122, 312

diuretics, 158, 312 in pregnancy, 312 vasodilators, 118, 312 hyperthermia, atropine poisoning and, 106, 202 hyperthyroidism, 244,

246-247 hypertonia, 226 hyperuricemia, 162, 316 hypnotics, 222-225

dependence, 222, 223 hypoglycemia, 92, 260 hypokalemia, 162, 163,

172, 173 hypophysis, 242-243, 250 hypotension, 118, 119, 314

treatment, 90, 314-315 hypothalamic releasing hormones, 242, 243 hypothalamus, 242, 250, 251

hypothermia, 238 hypothyroidism, 244 hypovolemic shock, 152

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