The antiandrogen cyproterone

acts as a competitive antagonist of T. In addition, it has progestin activity whereby it inhibits gonadotropin secretion (p. 254). Indications: in men, inhibition of sex drive in hypersexuality; prostatic cancer. In women: treatment of virilization, with potential utilization of the gestagenic contraceptive effect.

Flutamide, an androgen receptor antagonist possessing a different chemical structure, lacks progestin activity.

Finasteride inhibits 5a-reductase, the enzyme converting T. into dihydro-testosterone (DHT). Thus, the androgen-ic stimulus is reduced in those tissues in which DHT is the active species (e.g., prostate). T.-dependent tissues or functions are not or hardly affected (e.g., skeletal muscle, negative feedback inhibition of gonadotropin secretion, and libido). Finasteride can be used in benign prostate hyperplasia to shrink the gland and, possibly, to improve micturition.

-propionate C - C -heptanoate 2 C - C - C - C - C - c| I |> Duration of effect 2 weeks

Testosterone rH'

Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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