8 Darifenacin

Tricyclic antidepressants, particularly imipramine, can also be used for treatment, facilitating urine storage, by both decreasing bladder contractility and by increasing outlet resistance. The 5HT/NE uptake inhibitor (SNRI) duloxetine (9) increases extracellular monoamine levels leading to contraction of the urethral sphincter to prevent urine leakage. Bethanechol (11) is another cholinergic agent used to treat bladder (detrusor) underactivity in individuals with incomplete bladder emptying.

Anxiety and Depression 101

Anxiety and Depression 101

Everything you ever wanted to know about. We have been discussing depression and anxiety and how different information that is out on the market only seems to target one particular cure for these two common conditions that seem to walk hand in hand.

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