Cee03310

Baclofen

Antalarmin

Valproate

Various naltrexone formulations

Disulfiram

Topiramate

Modafinil

Cocaine vaccine (TA-C)

Quetiapine

Selegiline g-Vinyl-GABA

Gabapentin

Tiagabine

Baclofen

Cabergoline

Adrogolide (DAS-431)

Tolcapone

Vigabatrin (GVG)

Ondansetron

Memantine

Sertraline

Isradipine

Citicoline

Dextroamphetamine Lobeline BP 897

Vanoxerine (GBR 12909) Enadoline (CI 977) Selegiline Rimonabant Methoxsalen

Nicotine conjugate vaccine (NicVax) Varenicline, SSR-591813, ABT 418 Various formulations of nicotine

GABA/glutamate m Opioid antagonist CB1 receptor antagonist NMDA receptor antagonist D1 receptor antagonist GABAb receptor agonist CRF1 Receptor antagonist Unknown mechanism m Opioid antagonist Unknown GABA/glutamate Unknown Cocaine

Dopamine D2/5HT2 antagonist MAO-B inhibitor GABA transaminase inhibitor Multiple mechanisms GABA transport inhibitor GABAb receptor agonist Dopamine D2 receptor agonist Dopamine D1-like receptor agonist COMT inhibitor

Irreversible GABA transaminase inhibitor 5HT3 receptor antagonist NMDA receptor antagonist Serotonin transporter inhibitor Calcium channel antagonist Enhanced phospholipid synthesis Dopamine releaser

Nicotinic receptor antagonist, inhibitor at the VMAT2

D3 receptor partial agonist

Dopamine transporter inhibitor

Opioid k receptor agonist

MAO-B inhibitor

CB1 receptor antagonist

CYP2A6 inhibitor that inhibits nicotine metabolism Nicotine

Nicotinic a4p2 agonists

Adapted from

reason for the poor compliance may result from naltrexone-induced dysphoric effects. Compliance with naltrexone treatment is higher among healthcare workers and parolees who by law can not participate in methadone clinics, and who are required to participate in treatment as a condition of their licensure.7

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