Clinical use

Sulfonylureas increase endogenous insulin secretion. Their efficacy, measured by the plasma glucose lowering effect, is greatest in individuals with newly diagnosed T2DM. Clinical studies have shown that sulfonylureas reduce mean FPG to 54-72 mgdL_ 1 and HbA1C levels by 1.5-2%. The benefit of sulfonylurea therapy depends on the initial degree of hyperglycemia, duration of diabetes (more effective in T2DM of shorter duration), and previous use of other oral hypoglycemic agents. Because many of the sulfonylurea metabolites are active, more conservative dosing is advised in any patient who may be at high risk for decreased hepatic metabolism or renal clearance of the active drug or metabolites.

Supplements For Diabetics

Supplements For Diabetics

All you need is a proper diet of fresh fruits and vegetables and get plenty of exercise and you'll be fine. Ever heard those words from your doctor? If that's all heshe recommends then you're missing out an important ingredient for health that he's not telling you. Fact is that you can adhere to the strictest diet, watch everything you eat and get the exercise of amarathon runner and still come down with diabetic complications. Diet, exercise and standard drug treatments simply aren't enough to help keep your diabetes under control.

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