The dominant effect of corticosteroids is anti-inflammatory - reducing the expression of inflammatory cytokines and adhesion molecules, and reducing the trafficking of inflammatory cells. At high doses, they may induce apoptosis in immune cells. Their effects are often transient. Further, frequent use of corticosteroids is associated with long-term adverse effects, such as osteoporosis, and their use has to be carefully managed. On the other hand, individual pulses of corticosteroids are relatively free from adverse effects.

Dealing With Back Pain

Dealing With Back Pain

Deal With Your Pain, Lead A Wonderful Life An Live Like A 'Normal' Person. Before I really start telling you anything about me or finding out anything about you, I want you to know that I sympathize with you. Not only is it one of the most painful experiences to have backpain. Not only is it the number one excuse for employees not coming into work. But perhaps just as significantly, it is something that I suffered from for years.

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