The dominant effect of corticosteroids is anti-inflammatory - reducing the expression of inflammatory cytokines and adhesion molecules, and reducing the trafficking of inflammatory cells. At high doses, they may induce apoptosis in immune cells. Their effects are often transient. Further, frequent use of corticosteroids is associated with long-term adverse effects, such as osteoporosis, and their use has to be carefully managed. On the other hand, individual pulses of corticosteroids are relatively free from adverse effects.

Back Pain Revealed

Back Pain Revealed

Tired Having Back Pains All The Time, But You Choose To Ignore It? Every year millions of people see their lives and favorite activities limited by back pain. They forego activities they once loved because of it and in some cases may not even be able to perform their job as well as they once could due to back pain.

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