Disease State

Epilepsy can be classified as idiopathic in origin when no etiology other than a genetic predisposition has been identified; symptomatic when epilepsy can be associated with trauma, e.g., poisoning, stroke, head injury or a brain lesion, Lennox-Gastaut syndrome, hippocampal sclerosis, and cerebral palsy; or cryptogenic where a symptomatic cause is suspected but unproven. Advances in the understanding of the genetics of epilepsy together with neuroimaging technologies have reduced the diagnosis of cryptogenic epilepsy. Approximately 70% of epilepsies can be attributed to a specific brain pathology. The many forms of epilepsy suggest that it is not a single disorder with a single molecular lesion but rather a spectrum of diseases.

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