Diuretics

Diuretics are the most common initial treatment for mild hypertension (Figure 7). Based on their site of action in the kidneys, diuretics can be classified into loop, thiazide, and potassium-sparing diuretics. Loop or high-ceiling diuretics,

Treatment of hypertension and associated endothelial dysfunction

Current treatment

1. Diuretics

3. Vasodilators

4. ACE inhibitors

5. Angiotensin receptor blockers

6. Calcium channel blockers

Future treatment

1. L-Arginine supplements

2. Endothelin receptor blockers

3. EETs mimetics

4. sEH inhibitors

5. HETE inhibitors

6. Antioxidants

Figure 6 Current and future treatment of renal dysfunction and hypertension.

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