Genetic risk factors

Numerous genetic risk factors, genes with multiple alleles, one of which may predispose an individual to disease, have been identified, which increase the likelihood of development of AD.21 A few recently identified AD-associated genetic risk factors are listed in Table 1. The first described with the highest risk association with disease to date is the E4 allele of the apolipoprotein E (APOE). This allele has been shown to influence Ab oligomerization and its

Table 1 Neurodegenerative disease characteristics





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Blood Pressure Health

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