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6.06.6.4 Primary Insomnia

6.06.6.4.1 Antidepressants

Tricyclic antidepressants (TCAs) and other antidepressants including amitriptyline, 28, trimipramine, 29, doxepine, 30, mirtazapine, 31, trazodone, 32, and nefazodone, 33, are used to treat insomnia,23 but their therapeutic hypnotic benefit derives from their sedative side effect profiles.

NMe2 28 Amitriptyline

NMe2 28 Amitriptyline

"NMe2 CH3

29 Trimipramine

NMe2

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