New Research Areas

Intensive investigation toward novel clinical candidates for treatment of drug addiction has ensued and many candidates with a diversity of mechanisms of action have been identified and are in various stages of preclinical and clinical development. A list of these potential medications is given in Table 6 with their chemical structures shown in Figure 8. These compounds have been identified based on their current clinical use and/or their mechanism of action which has been deemed pertinent to drug addiction, as discussed in Section 6.07.2. Their efficacy in treating drug addiction remains to be established but in all cases, a proof of concept in animal models has been provided.8'51'54'75'76

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