Compound 57a - neuroprotection only

Figure 12 Chemical structures of the tripeptide thyrotropin-releasing hormone (TRH) and analog. TRH and the synthetic analog YM-14673 possesses endocrine, analeptic, autonomic, and neuroprotective effects. The neuroprotective effects of TRH are lost in the case of MK-771, which retains the endocrine, analeptic, and autonomic properties. In contrast, the diiodoimidazle analogs of TRH (2,4-diiodo-TRH) and YM-14673 (Compound 53a), and diketopiperazine-containing Compound 57A are selective for neuroprotective effects of TRH only.85

Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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