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Stefano Evangelista PhD has a long history of research in gastrointestinal pharmacology at both academic and private institutes of research. He has successfully contributed to the characterization of the role of several neuropeptides in gastrointestinal function, and participated to the development of tachykinin antagonists. He is a member of a group developing basic research in the field of capsaicin-sensitive neurons, with pioneering input in the recognition of the function of neuropeptides such as calcitonin gene-related peptide, substance P, and neurokinin A in the gastrointestinal tract. Working in the pharmaceutical industry, first in the discovery section and then in development, he has made major contributions to the furthering of knowledge on the mechanism of action of drugs, from molecular pharmacology to the clinic. He is the author of 120 papers, and between 1993 and the present he has been a referee for 18 international journals. He is currently working in preclinical development for Menarini Ricerche, and has developed numerous collaborations with academic groups with significant input in exploratory pharmacology to find new and relevant targets for the treatment of irritable bowel syndrome.

© 2007 Elsevier Ltd. All Rights Reserved Comprehensive Medicinal Chemistry II

No part of this publication may be reproduced, stored in any retrieval system or transmitted ISBN (set): 0-08-044513-6 in any form by any means electronic, electrostatic, magnetic tape, mechanical, photocopying, recording or otherwise, without permission in writing from the publishers ISBN (Volume 6) 0-08-044519-5; pp. 597-601

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