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Mike G Wyllie, BSc, PhD After spells as a lecturer in Edinburgh and at Wyeth Laboratories, Dr Wyllie joined Pfizer in 1984. During the next decade as Director of Biology he was responsible for building up the Pfizer urology and sexual health groups that resulted in the development of doxazosin, sertraline, sildenafil, and darifenacin. Over the period 1994-98 during which both Cardura and Viagra were launched he was Director of Urology at Pfizer, NY. Subsequently, Dr Wyllie created Urodoc Ltd, a strategic planning and medical education company (, and a specialist urology biopharmaceutics company specializing in urological product development, Plethora Solution PLC ( He is also chief scientific officer for the medical technology company Zi Medical PLC (

Dr Wyllie has written in excess of 100 articles and is the inventor of almost 90 patents. He is an Assistant Editor (Sexual Medicine Section) of the British Journal of Urology (BJU International) and a member of the European Association Of Urology (EAU), American Urological Association (AUA), and the British Association of Urological Surgeons (BAUS).

© 2007 Elsevier Ltd. All Rights Reserved Comprehensive Medidnal Chemistry II

No part of this publication may be reproduced, stored in any retrieval system or transmitted ISBN (set): 0-08-044513-6 in any form by any means electronic, electrostatic, magnetic tape, mechanical, photocopying, recording or otherwise, without permission in writing from the publishers ISBN (Volume 6) 0-08-044519-5; pp. 551-573

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