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Biography

Edward D Hall received his PhD in neuropharmacology from the Cornell University Graduate School of Medical Sciences in 1976. After completing a postdoctoral fellowship at Cornell University Medical College, he joined the Northeastern Ohio Universities College of Medicine, where he rose to the rank of associate professor of pharmacology. In 1982, he moved to The Upjohn Company, where he initiated and led an effort over many years to discover and develop agents for the treatment of traumatic brain and spinal cord injury and stroke. He played a leading role in the development of high-dose methylprednisolone therapy for acute spinal cord injury, demonstrating that its neuroprotective action involves inhibition of posttraumatic lipid peroxidation. For this work he received the Upjohn Achievement in Science and Medicine Award in 1991. In addition, he was co-discoverer of the 21-aminosteroids (lazaroids), including tirilazad mesylate. In 1997, Dr Hall left Upjohn and joined Parke-Davis Pharmaceutical Research, which is now part of Pfizer Global Research and Development (PGRD). In 2001, he was appointed senior director of CNS Pharmacology at PGRD-Ann Arbor. On July 1, 2002, he joined the University of Kentucky Medical Center, where he is director of the Spinal Cord and Brain Injury Research Center (SCoBIRC) and professor of Anatomy and Neurobiology, Neurosurgery and Neurology. His ongoing research is funded by the NIH and by the Kentucky Spinal Cord & Head Injury Research Trust.

© 2007 Elsevier Ltd. All Rights Reserved Comprehensive 'Medicinal Chemistry II

No part of this publication may be reproduced, stored in any retrieval system or transmitted ISBN (set): 0-08-044513-6 in any form by any means electronic, electrostatic, magnetic tape, mechanical, photocopying, recording or otherwise, without permission in writing from the publishers ISBN (Volume 6) 0-08-044519-5; pp. 253-277

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