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Biographies

Donna Bozyczko-Coyne, PhD, received her doctorate in Biochemistry (1988) from the University of Pennsylvania, School of Medicine, with a focus on neurosciences. Under the direction of Dr Alan F Horwitz, she studied the role of cell adhesion molecules (integrins) in the development of the neuromuscular junction and in neurite outgrowth. Continuing an interest in developmental neurosciences, she conducted postdoctoral studies with Dr Art Morris at the Wistar Institute, Philadelphia, PA, studying the role of IGF-1 in the development of the oligodendrocyte lineage. In 1990, Dr Bozyczko-Coyne accepted a Research Scientist position at Cephalon, Inc., where she has conducted drug discovery research in the therapeutic areas of stroke/ischemic neuronal damage, Parkinson's and Alzheimer's diseases. In 2000, Dr Bozyczko-Coyne became Director of Neurobiology and is, today, Director of Research and Development Strategic Coordination at Cephalon, Inc.

Michael Williams, PhD DSc, received his PhD (1974) from the Institute of Psychiatry and his Doctor of Science degree in Pharmacology (1987), both from the University of London. Dr Williams has worked in the US-based pharmaceutical industry for 30 years at Merck, Sharp, and Dohme Research Laboratories, Nova Pharmaceutical, CIBA-Geigy, and Abbott Laboratories. He retired from Abbott Laboratories in 2000 and, after serving as a consultant with various biotechnology/pharmaceutical companies in the US and Europe, joined Cephalon, Inc. in West Chester in 2003, where he is Vice President of Worldwide Discovery Research. He has published some 300 articles, book chapters, and reviews, and is Adjunct Professor in the Department of Molecular Pharmacology and Biological Chemistry at the Feinberg School of Medicine, Northwestern University, Chicago, IL.

© 2007 Elsevier Ltd. All Rights Reserved Comprehensive Medicinal Chemistry II

No part of this publication may be reproduced, stored in any retrieval system or transmitted ISBN (set): 0-08-044513-6 in any form by any means electronic, electrostatic, magnetic tape, mechanical, photocopying, recording or otherwise, without permission in writing from the publishers ISBN (Volume 6) 0-08-044519-5; pp. 193-228

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