Unmet Medical Needs

As with AD, a large unmet medical need in PD is the development of drugs that slow disease progression. A paucity of established biomarkers for early disease diagnosis confounds indicators of treatment efficacy. This is particularly evident for drugs in which there is no symptomatic benefit demonstrated, since clinical trials of long duration (~ 18-24 months) need to be carried out with large patient numbers in order to power the study appropriately to see perhaps small but significant effects. For drugs that do have symptomatic effects, neuroprotective events of the compounds can be established using a drug wash-out study design. This strategy has been used for selegine and pramipexole, but as of yet no drug is approved and has US FDA labeling indicative of a disease-modifying effect.

Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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