Introduction

Cancer can be considered a general term that covers a plethora of different malignancies. These pathogenic conditions are characterized by uncontrolled cellular proliferation and growth, and under special conditions, tumor cell migration, invasion, and spreading to other organs and tissues. Different factors and conditions can transform normal cells into cancerous ones by altering the normal function of a wide spectrum of regulatory, apoptotic, and signal transduction pathways. The complexity of these biochemical processes and networks represent a major challenge in the elucidation of the changes that must occur in order to initiate and maintain cancer progression. Although our understanding of the biology of human cancer is not fully complete, numerous genes and proteins that are causally involved in the initiation and progression of cancer have been identified in the past few years, but due to space constraints and the broad scope of this topic, we have emphasized here the most recent advances in our understanding of the principles underlying tumor cell transformation, growth, survival, invasion, and metastasis. To start with, we briefly cover the epidemiology of cancers and provide information about the available treatment modalities for the four major types of cancer in adults (breast, lung, colorectal, and prostate). After this, different biological processes and signal transduction pathways that are altered in cancer cells or used by the malignant cells to spread to other organs and tissues are reviewed. Throughout the chapter, several review articles on individual topics have been included, and the reader is referred to the most recent publications in the text.

10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

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