Summary and Future Directions

The first kinase inhibitors have established themselves alongside existing agents in the treatment of many cancers. This position has only been reached through a huge global investment by scientists and clinicians, companies, and research institutes, and has challenged the way in which novel anticancer drugs are developed. The search for novel protein kinase inhibitors may constitute more than half of the current medicinal chemistry effort in oncology. The lives of millions of current and future cancer patients will be touched by the ability of medicinal chemists, and their partners in drug discovery, to learn lessons from the compounds described in this review. Future progress in the field requires exploitation of the burgeoning structural and bioinformatic data, the conquering of drug-induced resistance, and the opening up of novel inhibitory paradigms, outside the ATP-binding site of active kinases.

10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

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