Table 1 Representative examples of the most commonly used anticancer agents and their mechanism of action

Generic name

Type of drug

Cyclophosphamide, cisplatin Doxorubicin, mitomycin

Methotrexate, fluorouracil, capecitabine, gemcitabine Paclitaxel

Tamoxifen, raloxifene Anastrozole, letrozole, examestane Goserelin, leuprolide

Trastuzumab, cetuximab, becacizumab Etoposide

Vincristine, vinorelbine

Leucovorin

Irinotecan

Flutamide, bicalutamide Zoledronic acid Imatinib, erlonitib

Alkylating agent3

Antibiotic3

Antimetabolite4

Taxanec

Antiestrogend

Aromatase inhibitor^

Luteinizing hormone-releasing hormone analogd

Gonadotropin-releasing hormone analogd

Monoclonal antibody

Topoisomerase II inhibitor*

Vinca alkaloidc

Vitamin derivative

Topoisomerase I inhibitor*

Antiandrogend

Bisphosphonic acid

Kinase inhibitor^

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