How Are Genes And Gene Products Associated With Go Terms

Genes and gene products can obviously be associated with GO terms by whomever wishes to do so. For the groups participating in the GO Consortium, some general rules concerning gene associations to GO have been formulated. A gene product may be annotated to zero or more nodes of each ontology, and may be annotated to any level within the ontology. A well-characterized RNA or protein might be annotated using very specific terms, whereas a little-studied gene product might be annotated using only...

Alternate Protocol 2 Finding Repeated Motifs In Dna Sequences With Meme

This protocol describes the use of MEME via the MEME Web interface or the command line to discover repeated motifs in a set of DNA sequences. It also discusses how to interpret the motifs and use them to search sequence databases. Command-line MEME works on many uniprocessor computers, some multiprocessor computers, and clusters that have the MPICH message-passing software installed. A list of supported operating systems and their manufacturers is available at (optional). Software Web browser...

Basic Protocol Searching Omim Over The Internet

OMIM may be accessed directly from the NCBI home page (http www.ncbi.nlm.nih.gov) by clicking on the OMIM link in the blue bar at the top of the page. This protocol describes accessing the Web site and entering search terms to retrieve OMIM records. It then briefly reviews the format of an OMIM record and guides the user through the numerous hyperlinks that are available. The search term synuclein will be used as an example throughout this protocol. Any Internet-connected computer Software...