Efferent mechanisms

Those regulating renal sodium excretion and controlling extracellular fluid volume

* Glomerular filtration rate

* Physical factors

At proximal tubule level Beyond proximal tubule level

* Humoral effector mechanisms Renin-angiotensin-aldosterone system Vasopressin

Catecholamines

Prostaglandins: PGE2, PGI2, thromboxane Kinin-kallikrein system Atrial natriuretic peptide (ANP) Endothelium-derived factors

* Renal sympathetic nerves

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