Enterohepatic circulation

The components of the enterohepatic cycle are the liver, biliary tract, intestine and the portal venous system. Ninety per cent to 95 % of the bile acids entering the gut are actively absorbed in the terminal ileum by a Na-anion co-transporter. The energy for uptake of bile acids is provided by a Na+/K+- ATPase located on the basolateral membrane of the enterocyte. Approximately 500-700 mg are lost per day in the faeces. This is replaced by hepatic synthesis.

There is a total bile acid pool of 2-5 g in the liver. Twenty to 30 g per day of bile acid enters the duodenum, i.e. the bile acid pool recycles 6-10 times in 24 hours through the enterohepatic circulation.

Was this article helpful?

0 0
Wake Up Now

Wake Up Now

For Those Who Can’t Wake Up On Time And Fatigue Throughout The Day. Now You Can Wake Up Early And Be Super Energetic Everyday.

Get My Free Ebook


Post a comment