Functions of phosphate

These include:

Formation of high energy compounds: e.g. ATP, creatinine phosphate; Formation of second messengers, e.g. cyclic AMP, inositol phosphates; Component of DNA/RNA, phospholipid membranes, bone; Phosphorylation (activation/inactivation) of enzymes; Intracellular anion.


This can be encountered in the following situations:

Factitious hypocalcaemia

Hypoalbuminaemia Hypomagnesaemia

True hypocalcaemia

Vitamin D deficiency or target organ resistance; Dietary deficiency or malabsorption; Impaired 25-hydroxylation: liver disease; Impaired 1 alpha-hydroxylation: renal failure; Accelerated loss: anticonvulsants; PTH deficiency or target organ resistance; Hyperphosphataemia;

Loss of calcium from the circulation: excessive deposition in the skeleton (osteoblastic metastases; hungry bone syndrome); chelation.

Was this article helpful?

0 0
Wake Up Now

Wake Up Now

For Those Who Can’t Wake Up On Time And Fatigue Throughout The Day. Now You Can Wake Up Early And Be Super Energetic Everyday.

Get My Free Ebook

Post a comment