Hormone receptors

Plasma membrane receptors are integral membrane proteins with three basic domains:

An extracellular ligand-binding domain;

A transmembrane domain, usually with seven spans of the membrane, with an exposed N-terminal and a C-terminal projecting into the cytosol; An intracellular or cytoplasmic domain. Intracellular receptors generally consist of a single polypeptide chain with: A variable -NH2 terminus domain;

A conserved deoxynucleic acid (DNA)-binding domain (response element), which is a zinc finger motif;

Receptors for molecules used in signalling

Receptors for lipid-soluble signalling molecules

Steroid hormone family of receptors; Catalytic, cytosolic receptors.

Receptors for water-soluble signalling molecules

Ligand-gated ion channel receptors; Catalytic, membrane receptors; Receptors coupled directly to a cytosolic enzyme; G-protein-coupled membrane receptors.

5 A variable hinge region;

Was this article helpful?

0 0
Tips and Tricks For Boosting Your Metabolism

Tips and Tricks For Boosting Your Metabolism

So maybe instead of being a pencil-neck dweeb, youre a bit of a fatty. Well, thats no problem either. Because this bonus will show you exactly how to burn that fat off AS you put on muscle. By boosting your metabolism and working out the way you normally do, you will get rid of all that chub and gain the hard, rippled muscles youve been dreaming of.

Get My Free Ebook


Post a comment