Peroxisomes microbodies

Peroxisomes are round or oval membrane-bound organelles, with an average diameter of 0.5 mm. They contain high concentrations of oxidative enzymes, i.e. catalase, D-amino oxidase and urate oxidase. Peroxisomes are abundant in the liver and kidneys.

Their functions include:

Synthesis of plasmalogens, important in cell membranes and myelin; Cholesterol synthesis; Bile acid synthesis;

Beta oxidation of fatty acids: the peroxisomal oxidation of ultra long-chain fatty acids is defective in X-linked adrenoleukodystrophy; Conversion of amino acids into glucose;

The reduction of hydrogen peroxide, preventing tissue damage; The prevention of excess synthesis of oxalate.

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